郝雪芳，女，博士，讲师。2012年7月毕业于河北大学高分子材料与工程专业，2012年9月至2018年6月就读于天津大学应用化学专业医用高分子材料方向，获工学硕士和博士学位。主持省级及以下项目两项，在Chem. Eng. J., Acta Biomater., ACS Appl. Mater. Interfaces, Biomater. Sci.等学术期刊发表SCI论文20余篇。
E-mail：hxf15175374404@126.com
研究方向
聚合物材料的合成
多功能基因/药物递送系统的设计、制备及应用研究
科研项目
1.内蒙古自治区高等学校科学研究重点项目，靶向仿生荧光纳米体系的构建及其在肿瘤成像和治疗中的研究（NJZZ20109），2020.01-2022.12，6万，结题，主持。
2.内蒙古自治区自然科学基金项目，pH响应性仿生药物递送系统抑制血管再狭窄的研究（2019BS08005），2019.01-2021.12，10万，结题，主持。
近年发表的代表性论文
1. Xuefang Hao*; Weiwei Gai; Yanping Zhang; Weitong Zhou; Yakai Feng*; Biomimetic and inflammation-targeted nanoparticles for rheumatoid arthritis therapy via M1-macrophages apoptosis and polarization, Materials & Design, 2024, 239: 112806.
2. Xuefang Hao*; Weiwei Gai; Yanping Zhang; Dandan Zhao; Weitong Zhou; Yakai Feng*; Peptide functionalized biomimetic gene complexes enhance specificity for vascular endothelial regeneration, Colloids and Surfaces B: Biointerfaces, 2024, 114020.
3. Xuefang Hao*; Qian Li; Recent Advances in Cell‐Based Nanotherapy for Cardiovascular Diseases, Macromolecular Bioscience, 2023, 23(7): 2200537.
4. Xuefang Hao*; Weiwei Gai; Feng Ji; Lina Wang; Jiadi Zhao; Fan Yang; Haixia Jiang; Yakai Feng*; Biomimetic and responsive nanoparticles loading JQ1 for dual-targeting treatment of vascular restenosis via multiple actions, Chemical Engineering Journal, 2022, 431(4):133452.
5. Xuefang Hao*; Weiwei Gai; Feng Ji; Jiadi Zhao; Dandan Sun; Fan Yang; Haixia Jiang; Yakai Feng*; Bovine serum albumin-based biomimetic gene complexes with specificity facilitate rapid re-endothelialization for anti-restenosis, Acta Biomaterialia, 2022, 142: 221-241.
6. Xuefang Hao*; Weiwei Gai; Lina Wang; Jiadi Zhao; Dandan Sun; Fan Yang; Haixia Jiang; Yakai Feng*; 5-Boronopicolinic acid-functionalized polymeric nanoparticles for targeting drug deliveryand enhanced tumor therapy, Materials Science & Engineering C, 2021, 119: 111553.
7. Weiwei Gai; Xuefang Hao*; Jiadi Zhao; Lina Wang; Jinghai Liu; Haixia Jiang; Hua Jin; Guoli Liu; Yakai Feng*; Delivery of benzoylaconitine using biodegradable nanoparticles to suppress inflammation via regulating NF-κB signaling, Colloids and Surfaces B: Biointerfaces, 2020, 191: 110980.
8. Xuefang Hao; Qian Li; Huaning Wang; Khan Muhammad; Jintang Guo; Xiangkui Ren; Changcan Shi; Shihai Xia; Wencheng Zhang; Yakai Feng; CAGW modified polymeric micelles with different hydrophobic cores for efficient gene delivery and capillary-like tube formation, ACS Biomater. Sci. Eng., 2018, 4: 2870-2878.
发明专利
1. 郝雪芳，盖微微，基于蛋白和血小板膜修饰的基因递送系统制备方法和应用，2022-12-13，中国，ZL202011403571.1
2. 郝雪芳，盖微微，一种多功能高效药物递送系统及其制备方法和应用，2023-08-11，中国，ZL202011606510.5
